Feared cholesterol, but it takes

Written By bopuluh on Kamis, 07 Juli 2011 | 00.13

Unhealthy lifestyles have made an enemy of human cholesterol. Yet, these substances are beneficial to brain and liver, and neural networks that exist in the human body. In fact, cholesterol plays a role in the formation of sex hormones.

Hearing the word cholesterol, our minds are most certainly directed to the executioners diseases such as heart disease, stroke, and so on. Opinion is increasingly shaped by the many advertisements of food products which gives the lure of "cholesterol free".

Excessive exposure, suggesting that cholesterol is a great enemy to human health. Really dangerous cholesterol?
Judging from history, cholesterol does give a bad record for the medical world. In 1908, experts have found that experimental animals fed meat, dairy fat, and eggs in excess will have fatty deposits on the walls of the arteries (blood vessels).

This causes the blood vessels become narrower, referred to as atherosclerosis. The process lasts very long and is a forerunner of stroke and heart attack. In 1913, some experts theorized that the fat is cholesterol deposition.

In 1916, Cornelius de Langen, a Dutch physician who was working in Indonesia, found that the number of native Indonesia is suffering from heart disease is lower than the Dutch people who lived in Indonesia.

He speculated that low cholesterol content among Indonesia due to a diet that contains more elements of the plant, rather than Dutch people who prefer meat and other animal foods.
At the end of World War II, the experts research in Scandinavia found that deaths from heart disease dropped dramatically during the war. This is due to decreased consumption of meat, milk, and eggs.

Currently the scientists found that people who suffer from heart disease, generally have higher cholesterol levels than healthy people.

In developed countries the consumption of high cholesterol (such as the United States), heart disease is one of the leading causes of death. Report of the American Heart Association (AHA) says that more than 100 million U.S. adults have cholesterol levels above the average, and 40 million of them have very high cholesterol levels. These conditions led to the death rate from heart disease and stroke reaches 500,000 people each year.
In 1976, the World Health Organization (WHO) reported that calcification of the heart due to cholesterol has been experienced by someone since the age of 20. Liming is increasingly thickened 3 percent annually.

Looking at the facts above, not surprisingly, many people identified cholesterol as something that is harmful to human health although opinions are not entirely correct. This paper will provide balanced information about the positive and negative effects of cholesterol.

Formed in the Body
Is cholesterol really is? Cholesterol is a typical product of animal metabolism. Cholesterol is found only in foods of animal origin such as meat, fish, eggs, milk, brain, and viscera. Judging from their chemical structure, cholesterol is a steroid group, ie a substance belonging to the class of lipids.

In humans, cholesterol itself can be synthesized in the body, namely in the liver, cortex, adrenal, skin, intestine, testis, stomach, muscle, adipose tissue, and brain. Approximately 17 percent of the dry weight of the brain composed of cholesterol. Thus, no cholesterol, brain structure can not be formed.

Although it is considered dangerous, cholesterol is still needed by the body. Average human takes 1100 milligrams of cholesterol per day to maintain cell walls and other physiological functions. Of these 25-40 percent (200-300 mg) are normally derived from food and the remainder is synthesized by the body.

If the amount of cholesterol in the body is less, the synthesis of cholesterol in the liver and intestines increased to meet the needs of other tissues and organs. Conversely, if the amount of cholesterol in the diet increased, the synthesis of cholesterol in the liver and intestine decreased.

Although the body can synthesize the needs cholesterol, cholesterol from food plays an important role because it is a major sterol in the human body, as well as the components of the cell surface and intracellular membranes.

Research in mice suggests, if there is only 0.05 percent of cholesterol in the diet, 70-80 percent of the cholesterol the body will be synthesized in the liver, small intestine, and adrenal glands. If the cholesterol content in foods rose 2 percent, kolsterol biosynthesis in the body dropped to 10-30 percent.

Cholesterol your body needs, among others, in the synthesis of bile acids needed for digestion of fat or oil, vitamin D synthesis, and as a component of cell membranes. Cholesterol has a crucial role in the body for not only forming cell membranes, but also other common biosynthetic precursor, including sex hormones and bile acids.

Cholesterol is a precursor of bile acids expenditures which are synthesized in the liver and serves to absorb triglycerides (triasilogliserol) and fat soluble vitamins from food, as well as precursors of steorid hormone, estrogen, and testosterone.

Another role of cholesterol, which helps nerve cells function. When no cholesterol, coordination of gestures and speech will be disrupted.

Types of Cholesterol
When the body is healthy and normal food consumption, body tends to maintain cholesterol balance. Diasup and synthesized cholesterol is converted into body tissue, hormones, and vitamins are then circulated into the body via the blood.

Cholesterol can not dissolve in blood. To be transported in the bloodstream, cholesterol along with other fats (triglycerides and phospholipids) must bind to proteins to form an insoluble compound, which is a lipoprotein.

Chylomicrons is a lipoprotein that transports fat to the liver. In the liver, fat ties are discussed, so that the element is formed back fat. Fatty acids that form will be used as an energy source or if the amount of excess will be stored in fatty tissue.

When cholesterol intake is insufficient, the liver cells will produce it. From the liver, cholesterol is transported by a lipoprotein called LDL (low density lipoprotein) to be brought to the body cells that need it, including the heart muscle cells, brain, and others in order to function properly.

Excess cholesterol will be transported back by a lipoprotein called HDL (high density lipoprotein) to take to heart and it will be broken down and thrown into the gallbladder as bile acids.

LDL contains more fat than the HDL, so that he will be floating in the blood. The main proteins that form the apo-B LDL (apolipoprotein-B). LDL is considered as bad fats because it can cause the attachment of cholesterol in the blood vessel wall.

LDL cholesterol is the largest carrier, which is about 60 percent of the total plasma cholesterol. Although often referred to as bad cholesterol, LDL has an important role, namely to bring sterols into peripheral tissues and membranes are used for construction or for the formation of steroid hormones.

HDL is the lipoprotein particles are dense and small, disintetis in the liver and intestine. HDL is often referred to as good fats because in its operations it clears excess cholesterol from blood vessel walls to transport it back to the liver. It is thought to be the main mechanism of HDL in protecting blood vessels against atherosclerosis.

These good fats can remove cholesterol from foam cells in atherosclerosis injury or protect LDL from oxidative modification. Low levels of HDL in the plasma will increase the risk of coronary heart disease. The main proteins that form of HDL is Apo-A (apolipoprotein).

HDL has less fat content and high density or heavier.

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